We are a group of geneticists, neuroscientists, and computer scientists who are passionate about discoveries of novel targets and models for mental illness through innovation at the confluence of computational, genetic, and genomic methods.
The Kumar Laboratory is located at the Jackson Laboratory in Bar Harbor, Maine. We study neural circuits in the brain whose misregulation leads to behavioral abnormalities including addiction, attention deficit hyperactivity disorder, and depression. Using mouse molecular genetics as a foundation, and a combination of computational, biochemistry, physiology, and imaging techniques, we dissect these complex conditions in mammals.
Primarily, we use functional genomic approaches in mice to identify genes and pathways that regulate these behaviors. We seek to develop better models of human diseases that can be used by the biomedical research community for therapeutics. Recently, we have applied machine learning and artificial intelligence methods to understand animal behavior at high spatial and temporal resolution, objectively, and over long periods of time. Our work has been published in numerous high impact journals such as Science, eLife, Nature Communications Biology, among others.
Latest Lab News and Blogs:
Tufts students in the Genetics and Neuroscience programs joined together on April 11 - April 13 in the annual effort to facilitate community between the Boston-based and Bar Harbor-based students. The three-day retreat featured student-talk sessions, student-poster...
Spectrum is a leading online magazine for autism research and treatment. Holly Barker from Spectrum interviewed Vivek and wrote this piece about our Cell Reports paper. ...
Press announcement here - the work will fund monitoring of ASD models using our long-term methods. We appreciate the support from SFARI (Simons Foundation Autism Research Initiative) which is one of the most innovative funding agencies for biomedical research....
A tour de force from Keith and Gautam. This is beautiful work. Full text is available here. https://www.cell.com/cell-reports/fulltext/S2211-1247(21)01740-X
Michelle Berger and Marina Santos have joined the Kumar Lab as Research Associates. More to come on their background and roles in the lab. WELCOME MARINA AND MICHELLE
A nice summary of our nociception paper by Janine. https://www.mousephenotype.org/news/jax-researchers-develop-new-automated-system-for-recording-pain-behaviour-in-mice/