Welcome

We are a group of geneticists, neuroscientists, and computer scientists who are passionate about discoveries of novel targets and models for mental illness through innovation at the confluence of computational, genetic, and genomic methods.

The Kumar Laboratory is located at the Jackson Laboratory in Bar Harbor, Maine. We study neural circuits in the brain whose misregulation leads to behavioral abnormalities including addiction, attention deficit hyperactivity disorder, and depression. Using mouse molecular genetics as a foundation, and a combination of computational, biochemistry, physiology, and imaging techniques, we dissect these complex conditions in mammals.

Primarily, we use functional genomic approaches in mice to identify genes and pathways that regulate these behaviors. We seek to develop better models of human diseases that can be used by the biomedical research community for therapeutics. Recently, we have applied machine learning and artificial intelligence methods to understand animal behavior at high spatial and temporal resolution, objectively, and over long periods of time. Our work has been published in numerous high impact journals such as Science, eLife, Nature Communications Biology, among others. 


 

 

 

Latest Lab News and Blogs:

Random Forests

Random Forests

The biggest perk of working at JAX besides getting to work in a team on exciting research problems is its location. The lab is situated between the Gulf of Maine and the mountains of Acadia National Park. The park offers innumerable outdoor activities. One such...

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Owning a reptile in a canine and feline companion world

Owning a reptile in a canine and feline companion world

Earlier this year, I decided to obtain a new addition to my home: a pet bearded dragon (Pogona vitticeps). It's been awhile since I've wanted a pet and finally made the move. While most people think that the pets of choice in america is either a cat or a dog, most...

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Kumar Lab receives a new grant from NIDA

Kumar Lab receives a new grant from NIDA

The Kumar Lab received a grant from NIDA to build new models of addiction. The press release is here https://www.jax.org/news-and-insights/2020/july/building-better-mouse-models-for-addiction-research The project summary is available here: PROJECT SUMMARY Addiction is...

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Kumar Lab hosts Dr. Eric Yttri for a virtual visit

Kumar Lab hosts Dr. Eric Yttri for a virtual visit

Dr. Yttri, from Carnegie Mellon University, Department of Biological Sciences, presented his lab's latest work from this paper. The paper uses unsupervised learning to understand the types of behaviors mice carry out. Dr. Yttri met with postdocs, engineers, and...

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PyTorch: keep the GPU busy

We all know it's important to use GPU resources efficiently, especially during inference. One easy and highly effective way to achieve this is to reorder some of your inference logic to exploit PyTorch's asynchronous GPU operations. This becomes especially important...

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HE Plots at a glance

Multivariate response data are routinely generated from experiments carried out in our lab. For example, several interrelated gait metrics such as stride length, step length, limb duty factor etc. are extracted from each stride of the mouse. The goal is to gain...

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