We are a group of geneticists, neuroscientists, and computer scientists who are passionate about discoveries of novel targets and models for mental illness through innovation at the confluence of computational, genetic, and genomic methods.
The Kumar Laboratory is located at the Jackson Laboratory in Bar Harbor, Maine. We study neural circuits in the brain whose misregulation leads to behavioral abnormalities including addiction, attention deficit hyperactivity disorder, and depression. Using mouse molecular genetics as a foundation, and a combination of computational, biochemistry, physiology, and imaging techniques, we dissect these complex conditions in mammals.
Primarily, we use functional genomic approaches in mice to identify genes and pathways that regulate these behaviors. We seek to develop better models of human diseases that can be used by the biomedical research community for therapeutics. Recently, we have applied machine learning and artificial intelligence methods to understand animal behavior at high spatial and temporal resolution, objectively, and over long periods of time. Our work has been published in numerous high impact journals such as Science, eLife, Nature Communications Biology, among others.
Latest Lab News and Blogs:
Vivek was on the Ric Tyler and George Hale show https://www.wvomfm.com/episode/ghrt-rewind-07-17-kumar-jax-lab-addiction-research-1100/
Vivek gave a lecture on the genetics of addiction at the Causeway Club on behalf of Acadia Family Center. The talk was attended by approximately 50 people. Dr. Dick Dimond also gave a talk preceding Vivek's talk.
Vivek attended and presented at the CTC meeting in UCSD. The CTC meeting is an annual meeting of complex trait geneticists who use model organisms. Vivek spoke on the use of computer vision to extract heritable ethological endophenotypes from mice. The meeting has...
The paper is currently under review and we hope it is published soon. Meanwhile, the preprint is available here. https://www.biorxiv.org/content/10.1101/648295v1
MDIBL hosted a meeting of researchers on the opioid crisis in Maine. The panel is part of the 46th Maine Biological and Medical Sciences Symposium (MBMSS), an annual statewide gathering at which students and scientists have the opportunity to network, collaborate,...