Welcome

We are a group of geneticists, neuroscientists, and computer scientists who are passionate about discoveries of novel targets and models for mental illness through innovation at the confluence of computational, genetic, and genomic methods.

The Kumar Laboratory is located at the Jackson Laboratory in Bar Harbor, Maine. We study neural circuits in the brain whose misregulation leads to behavioral abnormalities including addiction, attention deficit hyperactivity disorder, and depression. Using mouse molecular genetics as a foundation, and a combination of computational, biochemistry, physiology, and imaging techniques, we dissect these complex conditions in mammals.

Primarily, we use functional genomic approaches in mice to identify genes and pathways that regulate these behaviors. We seek to develop better models of human diseases that can be used by the biomedical research community for therapeutics. Recently, we have applied machine learning and artificial intelligence methods to understand animal behavior at high spatial and temporal resolution, objectively, and over long periods of time. Our work has been published in numerous high impact journals such as Science, eLife, Nature Communications Biology, among others. 


 

 

 

Latest Lab News and Blogs:

Opinion – Collaboration without collaborators

Recently, I got a golden opportunity to be at NIDA headquarters attending a meeting where leading scientists in the field of addiction were discussing the face validity of different behavioral assays on animal models to study aspects of human addiction. The discussion...

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Circadian and Sleep Research Support by NIH

Circadian and Sleep Research Support by NIH

I was part of a special emphasis study section last week titled - "Circadian Patterns of Gene Expression Associated with Disease" for RFA-HL-20-016. The RFA was sponsored by NHLBI and NIDA, so most of the proposals revolved around priorities of these two ICs.  Program...

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Transitioning from college to the lab

I finished my last semester of college pulling 3 AM thesis-writing sessions at the only restaurant that stayed open that late, chugging black teas and occasionally doing aerobics outside, making the other patrons uncomfortable. After turning in 98 pages of ramblings...

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Singularity Container Efficiency Benchmark

Singularity is a relatively new tool that extends docker-style containerized compute into the hands of researchers on compute clusters. For security reasons, most compute clusters did not allow docker containers, and would require any software to be installed by...

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Vivek attends the 2020 NIDA genetics consortium meeting

Vivek attends the 2020 NIDA genetics consortium meeting

Vivek and Arojit attended the NIDA genetics meeting in Bethesda, MD. They presented two posters. Vivek presented our work on cloning of a mutation that regulates cocaine responses. This is a new gene that has not been linked to cocaine responses.  Abstract from the...

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Vivek gives lecture at Dartmouth

Vivek gives lecture at Dartmouth

Vivek was invited to give a seminar at Dartmouth University by Dr. Gio Bosco and his postdoctoral fellow Shiva Sathyanarayana. Vivek spoke about the lab's work on Cyfip2 (work of postdoctoral Arojit Mitra, Kyungin Kim, and others). He also spoke about the lab's...

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